hrp0095p1-59 | Diabetes and Insulin | ESPE2022

Type 1 diabetes glycated haemoglobin outcomes did not differ by insulin regimen in two large Cambodian tertiary hospitals

May Ng Sze , IV Malene , Yay Chantana , Chhun Khun Leang , Manet Ban , Martin Tyla , Lek Ngee

Introduction: Action 4 Diabetes (A4D) is a UK non-profit organisation which has been providing free insulin and self-monitoring blood glucose test kits for children and young people (CYP) with type 1 diabetes (T1D) in Cambodia’s 2 large tertiary hospitals-Kantha Bopha II Hospital based in Phnom Penh (KB2H) and Jayavarman VII Hospital based in Siem Reap (J7H), since July 2018 and January 2020, respectively.Objective:</strong...

hrp0097p1-59 | Fat, Metabolism and Obesity | ESPE2023

Diagnostic value of soluble LEPR levels in the serum of patients with disease-causing biallelic LEPR variants

Zorn Stefanie , Tews Daniel , von Schnurbein Julia , Flehmig Bertram , Pridzun Lutz , Wabitsch Martin , Malene IV , Chantana Yay , Khun Leang Chhun , Ban Manet , Tyla Martin , Ngee Lek

Introduction: The soluble leptin receptor (sLR) is the main binding protein of leptin in the serum. It reflects the amount of membrane-bound leptin receptors (LEPR) as the sLR is produced by proteolytic cleavage of the extracellular domain of membrane-bound LEPR. Low sLR but high leptin levels were measured in patients with severe obesity. In patients with monogenic obesity caused by biallelic LEPR variants, sLR levels were found to be either undetect...

hrp0095p1-58 | Diabetes and Insulin | ESPE2022

Developing a digital Southeast Asia Type 1 diabetes healthcare educational platform in local languages during the pandemic

May Ng Sze , IV Malene , Khue Nguyen Thy , Le Khuong , Xian Lucas Lim Yang , Lek Ngee , Anuar Zaini Azriyanti , Seal Samantha , Yun Tange Steffen , Charlotte Ficheroulle Anne , Toomey Charles

Introduction: Action4Diabetes (A4D) is a non-profit UK organisation formed in 2016 that is making sustainable and scalable progress to provide quality Type 1 diabetes (T1D) healthcare in Southeast Asia (SEA). A4D provides comprehensive partnership programmes through a Memorandum of Understanding (MOU) signed with the governments in SEA that guarantees ongoing supplies of free insulin, blood glucose testing, HbA1c tests and hospital emergency funds in low-middl...